1. If this was a show about and called Superman instead.
2. If Supergirl wasn't Melissa Benoist
3. If Supergirl was more her mainstream teen brat personality rather than the kind altruistic adult as shown in this series.
4. Some supporting characters were cast differently
5. If the FX was significantly worse.
6. If it was as dark as Arrow.
So, my answers,
1. Yeah. Although now that I've seen this, I prefer a show about Supergirl.
2. Now that I've seen her act Kara, hell no. But if I didn't know, then yeah.
3. No.
4. Yes, probably. But again now that I've seen this I like the way it is.
5. Yes. But it would put a dent in my enjoyment.
6. Probably not, or at least I wouldn't like this nearly as much. Fiction is currently saturated with dark and aggresive female characters.